Isonipecotamide,C6H12N2O,CAS 39546-32-2

39546-32-2

Properties
Synonyms: Hexahydroisonicotinamide, Piperidine-4-carboxamide
CAS Number: 39546-32-2
Formula: C6H12N2O
Formula Weight: 128.18
Melting point: 148-149°
Sensitivity: Hygroscopic
Solubility: Soluble in water
Purity: 99%

Applications
Isonipecotamide is used as a reactant for the preparation of Survival motor neuron (SMN) protein modulators, orally available naphthyridine protein kinase D inhibitors and heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase. It is also used to prepare phosphodiesterase 5 inhibitors. It is also used as a reactant for identification of small molecular inhibitors of importin-beta mediated nuclear import. It is also used as a fluorenylmethyloxycarbonyl – deprotection agent in organic synthesis.

Notes
Moisture sensitive. Hygroscopic. Incompatible with strong oxidizing agents.

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