Methyl piperidine-4-carboxylate,C7H13NO2,CAS 2971-79-1

2971-79-1

Properties
Synonyms: Piperidine-4-carboxylic acid methyl ester, Methyl isonipecotate
CAS Number: 2971-79-1
Formula: C7H13NO2
Formula Weight: 143.18
Boiling Point: 85-90°
Flash Point: 89°(192°F)
Density: 1.06
Refractive Index: 1.4650
Solubility: Slightly soluble in water
Purity: 99%

Applications
Methyl piperidine-4-carboxylate is a reactant for C-2 arylation of piperidines through directed transition metal-catalyzed sp3 C-H activation. It is used as a reactant for synthesis of antitubercular agents, aminopyrazine inhibitors, orally available naphthyridine protein kinase D inhibitors and a scalable catalyst from asymmetric hydrogenation of sterically demanding aryl enamide.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.

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