Ethyl isonipecotate,C8H15NO2,CAS 1126-09-6
|Synonyms||Ethyl piperidine-4-carboxylate, H-DL-Inp-OEt|
|Solubility||Fully miscible with water|
It is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates.
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Store at room temperature. Incompatible with strong oxidizing agents.
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